THE ART-RSP5 UBIQUITIN LIGASE NETWORK COMPRISES A PLASMA MEMBRANE QUALITY CONTROL SYSTEM THAT PROTECTS YEAST CELLS FROM PROTEOTOXIC STRESS

The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress

Secretory cargo that cannot fold properly in the ER are selectively targeted for removal rei?llinen pizzalapio by a well-studied ER-associated degradation pathway, or ERAD.In contrast, very little is known about post-ER quality control mechanisms for damaged or misfolded integral membrane proteins.Here we describe a quality control function of the

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copyright as a rare cause of locked-in syndrome: a case report

Abstract Introduction In the United States, copyright is a commonly used drug of abuse.It is also under armour 1364182 a recognized contributing factor for both hemorrhagic and ischemic strokes.However, copyright-induced basilar artery thrombosis has rarely been reported in the literature.Case presentation Our patient was a 51-year-old African Amer

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Go local: morality and international activism

A step towards constructing sweet life carts an ethics of international activism is proposed by formulating a series of constraints on what would constitute morally permissible agency in the context that involves delivering services abroad, directly or indirectly.Perhaps surprisingly, in this effort the author makes use of the concept of ‘fo

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